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sclerosis

/skləˈroʊsəs/
IPA guide

Someone is diagnosed with the condition sclerosis when a part of their body becomes unusually hardened. A diet that's too high in cholesterol can cause sclerosis of the arteries.

In many cases of sclerosis, the stiffening of tissue in organs, nerves, or arteries happens when it's gradually replaced with harder connective tissue. One of the most common forms of sclerosis is called multiple sclerosis, or MS. In this disorder, nerve cells in the spinal cord and brain are affected. Eventually patients with multiple sclerosis experience lack of coordination, numbness, and other symptoms. The Greek root is skleros, or "hard."

Definitions of sclerosis
  1. noun
    any pathological hardening or thickening of tissue
    synonyms: induration
    see moresee less
    types:
    MS, disseminated multiple sclerosis, disseminated sclerosis, multiple sclerosis
    a chronic progressive nervous disorder involving loss of myelin sheath around certain nerve fibers
    ALS, Lou Gehrig's disease, amyotrophic lateral sclerosis
    thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cord; results in progressive muscle atrophy that starts in the limbs
    arteriolosclerosis
    sclerosis of the arterioles
    osteosclerosis
    abnormal hardening or eburnation of bone
    atherosclerosis, coronary artery disease
    a stage of arteriosclerosis involving fatty deposits (atheromas) inside the arterial walls, thus narrowing the arteries
    arteriosclerosis obliterans
    a stage of arteriosclerosis involving closure of blood vessels
    type of:
    pathology
    any deviation from a healthy or normal condition
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