Druthers means free choice or preference. When you have your druthers, you can do what you want.
The word druthers always appears in the plural form and usually in a phrase like "If I had my druthers..." It refers to a preference, wish, or desire. If you had your druthers, maybe you would sleep till 11 every day. If you had your druthers, maybe you would live in Australia. The word druthers evolved from a pronunciation of the phrase I’d rather, which should help you remember the meaning: Your druthers are the things you’d rather do.