If one thing is the exact opposite of something else, they're diametrically opposed. Here, diametrically is used to mean "totally" or "completely."
Diametrically is an unusual word — it's only used to modify the adjective opposed. When you describe two things that couldn't be more different from each other, you can say they're diametrically opposed. Is your brother a cheerful, optimistic person, while your sister is cranky and gloomy? Then they're diametrically opposed. This word comes from diameter, a line through a circle, in the sense that two points at either end of a diameter are directly opposite each other.