Other forms: depleted; depleting; depletes
To deplete is to use up or consume a limited resource. Visiting relatives might deplete your refrigerator of food, or a pestering friend might deplete your patience.
The verb deplete is used like “to drain.” A long, exhausting day can deplete your body of energy and a summer drought can deplete a region’s water supply. If you deplete your body of hydration after a lot of exercise, be sure to replete yourself with a nice glass of water.