If you're worried or concerned about something, you're bothered. You might see a bothered expression on your friend’s face if you spill soda all over her sweatshirt.
If you can’t be bothered to do something, you’re not doing it. If you feel bothered, something is getting on your nerves. This adjective is good for describing a range of emotions, from annoyance to worry, and it stems from an Anglo-Irish word meaning "noise." If you're "hot and bothered," you're extremely upset, anxious, or rattled.